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Friday, May 1, 2015
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2:00 PM
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3:00 PM
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Joint BioMedical Engineering / BioTech (BMEBT) and Mechanical Engineering (MNE) Seminar
- Location: Textiles Building 101E
- Contact: BMEBT Seminar Series
- Description: SPEAKER:
Ms. Manisha Jassal, BMEBT Program Doctoral Student at UMass Dartmouth
TOPIC:
Electrospun Fibers: Small Size, Big Impact
ABSTRACT:
Tissue regeneration relies on building carefully crafted scaffold material in the micron-submicron scale and imparting specific functionality to the scaffold material surface in order to mimic the in vivo environment closely in terms of chemical composition, morphology, and surface functional groups. Fibrous meshes with structural features at the micron-submicron level for ideal 3D tissue regeneration scaffolds can be an inexpensive scale up option. Bio-inert polymers lack the functional motifs for specific bioactivity; however, functionalization of the scaffolds can provide biological functions to actively induce tissue regeneration and promote cell adhesion by targeting specific cell-matrix interactions. It is therefore important to characterize the scaffolds and understand the relationship between the efficacy of the functionalization, the surface properties of the scaffolds, and their biological performance.
Another aspect of polymer functionalization is to target controlled drug delivery. Controlled drug delivery is required to improve the therapeutic efficacy of the drug and to reduce the potential toxic effects by delivering the drug at a rate governed by the physiological need of the site of action. Electrospun polymeric fibers have gained wide spread attention as potential drug delivery system because the drug release profile can be controlled by altering scaffold properties as composition, fiber morphology, porosity, surface coating, and form/state of drug molecule.
In the current study, poly(caprolactone) (PCL) fibers were fabricated by electrospinning, followed by various treatments to introduce functional groups on the fiber surface. The functionalized electrospun PCL fibers were characterized through scanning electron microscopy, x-ray photoelectron spectroscopy and gel permeation chromatography and the cellular response was studied for these scaffolds. Also, the functional groups introduced via hydrolysis (-COOH) can be ionized by manipulation of pH to impart a negative charge to the fiber surface.
Similarly, doxorubicin hydrochloride (DOX), an FDA approved anticancer drug, could be ionized to impart a positive charge at certain pH. The pH-sensitivity of both the materials was utilized to bind DOX electrostatically to the functionalized PCL fibers, with an aim to create pH-responsive drug delivery vehicle for targeted site-specific delivery of DOX.
Results indicate successful electrostatic binding of DOX to functionalized electrospun PCL fibers, a high drug payload and the drug delivery response can be modulated by introduction of suitable stimuli (pH in this case). Future work would concentrate on a formulation of a composite drug delivery vehicle combining electrospun scaffolds with poly(vinyl alcohol) (PVA) hydrogels that can release acid near the scaffolds to trigger drug release by changing the pH of the surrounding area.
Brief BIO:
Manisha Jassal is a doctoral student in BMEBT program at University of Massachusetts Dartmouth. She has received her Bachelor in Textile Technology from National Institute of Technology, Jalandhar, India, Master in Textile Technology from The Technological Institute of Textile & Sciences, Bhiwani, India and Master in Science (BMEBT) at UMass Dartmouth. Her research focuses on functionalization and characterization of sub-micron sized electrospun fibers for applications such as tissue engineering, environmental engineering and drug delivery. Her work has been published in different textile, tissue engineering and environmental engineering journals.
For more information please contact Dr. Mehdi Raessi, MNE Seminar Coordinator
(mraessi@umassd.edu, 508-999-8496).
Light refreshments will be served.
All are welcome. First year MNE MS students are required to attend; all MNE students are encouraged to attend.
- Topical Areas: Students, Bioengineering, College of Engineering, Mechanical Engineering, Lectures and Seminars
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4/15
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5/13
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Online Teaching and Learning Strategies
- Location: Online
- Contact: CITS Instructional Development
- Description: In this course, we will introduce you to current research and best practices for both online and blended teaching as well as showcase examples of successful teaching strategies for both methodologies. Throughout the course you will work both independently and collaboratively with your peers to gain valuable online course transition experience and develop strategies in online teaching and learning. As a participant, you will learn both pedagogical aspects of teaching online as well as how to use and incorporate many of the tools available in the myCourses Learning Management System used at UMD. The ultimate goal of the course is to have you begin planning, organizing and building the course you eventually plan to teach. In addition, this course will introduce you to tools that will teach you how to self-assess course site design to ensure student ease of access to course content and to facilitate more streamlined student learning and retention.
Visit the Online Teaching Guide to learn more about getting started with teaching online.
- Link: http://instructionaldev.umassd.wikispaces.net/Online+Teaching+Guide
- Topical Areas: Training, Workshop, audience: Faculty, topic: Faculty Development
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2:00 PM
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4:00 PM
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Master of Science Thesis Defense: Benjamin W. Lee
- Location: Science & Engineering Building, Lester W. Cory Conference Room: Room 213A
- Cost: Free
- Contact: ECE: Electrical & Computer Engineering Department
- Description: TOPIC: CLASS D POWER AMPLIFIER FOR DRIVING A PIEZOELECTRIC TRANSDUCER
LOCATION: Lester W. Cory Conference Room, Science & Engineering Building (Group II), Room 213A
ABSTRACT:
A class D power amplifier was developed and tested. The intended load is a piezoelectric transducer but other loads may be used with the amplifier design. The target specifications of the amplifier are 300 W power delivered to a 4 Ω resistive load, a frequency response of 1 kHz to 40 kHz, and a THD of 2% or lower. The design of the amplifier utilizes BD modulation, a MOSFET H-bridge, and dominant-pole compensated pre-filter voltage feedback. The class D amplifier was implemented on a printed circuit board (PCB). The PCB was assembled and tested and confirmed to meet the target specifications.
NOTE: All ECE Graduate Students are ENCOURAGED to attend.
All interested parties are invited to attend. Open to the public.
Advisor: Dr. David A. Brown
Committee Members: Dr. Robert Helgeland and Dr. David Rancour, Department of Electrical & Computer Engineering and Dr. Corey Bachand, BTech Acoustics LLC
*For further information, please contact Dr. David Brown via email at dbrown@umassd.edu.
- Topical Areas: General Public, University Community, Electrical and Computer Engineering
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9:00 AM
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4:00 PM
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Fidelity Representative on Campus
- Location: > See description for location
- Contact: > See Description for contact information
- Description: Individual counseling sessions regarding financial/retirement planning. You can discuss your personal financial situation with an experienced Fidelity consultant on a confidential basis. They are available to discuss how to help you achieve your financial goals by investing in financial solutions such as mutual funds, brokerage, life insurance and annuities.
Please contact Diana Valsky @ diana.valsky@fmr.com or 617-777-4770 to schedule an appointment.
Appointments will be held in CCB room 306.
- Topical Areas: Faculty, Staff and Administrators, Human Resources
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12:00 PM
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2:00 PM
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Indic Studies Patanjali Lecture" Poetry as a Means of Self-betterment"
- Location: Violette Research Building
, 285 Old Westport Road, Dartmouth, MA
- Contact: Center for Indic Studies
- Description: Center for Indic Studies announces:
Patanjali Lecture
"(Sanskrit) Poetry as a Means of Self-betterment: Some Thoughts from India's Classical Traditions"
Speaker: David Buchta, Brown University
Friday, May 1st 2015
Time: 12-2pm
Venue: Indic Studies Conference Room - Viollette 201
The humanities, including the study and composition of poetry, have come to be undervalued in contemporary society. Sanskrit poeticians offer an important corrective, making claims about the ability of poetry to function as a means of self-betterment, from developing insight into the ways of the world to the attainment of transcendent spiritual joy. The great grammarian, Patanjali, made claims for the particularly powerful nature of the Sanskrit language, claims which might broadened to apply to refined language more generally. In his talk, Dr. Buchta will consider these various claims and provide illustrative examples from the great Sanskrit poets.
For further information see contact: 508-999-8470/pwaknis@umassd.edu
- Topical Areas: Faculty, General Public, Staff and Administrators, Students, Students, Graduate, Students, Law, Students, Undergraduate, University Community
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4/11
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5/17
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2015 MFA Thesis Exhibition
- Location: Star Store, New Bedford
, Purchase Street, New Bedford
- Cost: Free admission
- Contact: University Art Gallery
- Description: Opening Reception: Saturday, April 11, 3-5 pm
The culmination of two to three years of intensive research and preparation of UMass Dartmouth MFA degree candidates in the visual art. Thesis work from Artisanry, Design, and Fine Arts at UMass Dartmouth on view from Apr 11 to May 17, 2015.
Exhibiting artists: Jessica Benzaquen, Mary Black, Andrea Abarca Coutts, Nick Heyl, Sarah Jenea Jones, George Manuel Karos, Amanda Kralovic, Xi Nan , Russell K. Prigodich, Alanna Schull, Anser Shaukat, Denise Sokolsky, Yishu Wang , Katie Wild, Ge Yang
University Art Gallery, Star Store Campus, College of Visual and Performing Arts, UMass Dartmouth, 715 Purchase Street, New Bedford, MA 02740
www.facebook.com/UMassDartmouthGalleries
Gallery exhibitions are open daily from 9:00 am to 6:00 pm and until 9:00 pm during AHA! Nights (every second Thursday each month).
- Link: umassd.edu/universityartgallery
- Topical Areas: Faculty, General Public, Staff and Administrators, Students, Students, Graduate, Students, Undergraduate, University Community, Art Education, Art History, Artisanry, College of Visual and Performing Arts, Fine Arts, Music, Visual Design, Exhibits, Visual Arts
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4/16
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4:00 PM
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Women Artists: The Untold Story (1890-1940)
- Location: CVPA: College of Visual and Performing Arts
, 285 Old Westport Road, Dartmouth, MA
- Contact: University Art Gallery
- Description: Women Artists: The Untold Story (1890-1940)
Exhibition Dates: April 16 - May 1
Opening Reception: Thursday, Apr 16, 4 - 6 PM with the Gallery Talk at 5 PM
Printmaking workshop: Thursday, April 23, 5-7 PM
Artists: Jessie Willcox Smith, Sarah Wyman Whitman, Eliza Draper Gardiner, Anna Brewster Richards, Blanche Ames, Theodosia Chase, Elizabeth Shippen Green, Emma Swan, Angela O'Leary, Allen Sisters, Mabel May Woodward, Grace Albee, Helen Watson Phelps, Alice Barbara Stephens, Ellen Dale Hale, Lena Newscastle and Mabel Dewit Eldred.
The University of Massachusetts Art History Department presents an exhibition entitled, Women Artists: The Untold Story (1890 - 1940). This show, which is part of the Senior Art History Capstone class at UMass Dartmouth, will feature paintings, illustrations, book cover designs and photographs created by professional late nineteenth and early twentieth century women artists from Philadelphia to Maine. The exhibition is open between April 15 and May 1, 2015 at the CVPA Campus Gallery, University of Massachusetts Dartmouth, 285 Old Westport Road, North Dartmouth, MA 02747. All are invited to the reception and gallery talk on Thursday, Apr 16, 4 - 6 PM.
The exhibition poses the question, "Why don't we know about these successful and prolific women artists of the Modernist period?" These women were accomplished artists, leaders within the art world and participated in many art related endeavors. They were involved in the establishment of art societies throughout North East, attended and taught students at prestigious art schools, studied aboard in Europe, and led successful and profitable business careers. For example, Jessie Willcox Smith illustrated every cover of Good Housekeeping from 1917 to April 1933, representing more than 292 illustrations; similar to Norman Rockwell's contribution to the Saturday Evening Post; yet recognition of Smith's professional accomplishments are often overlooked within traditional canon of art history. This is just one story of many that will be explored in the exhibition.
The exhibition is a project of the Art History Senior Seminar class, composed of sixteen art history upperclassmen. Through this course students applied their academic and professional knowledge to a real world experience. Students expanded their skill-sets within the fields of art history, art, design and museum studies, through their exhibition research, writing, interpretation, exhibition and graphic design, collection care, and visitor relations. Students also learned to work collaboratively, writing and editing the catalog, developing the exhibition design, installing the exhibition and developing public programming.
We would like to thank those individuals who generously loaned works from their private collections and to those institutions including Providence Art Club, Bert Gallery, Providence Athenaeum, Boston Public Library, Smith College, UMass Amherst and New Bedford Public Library who agreed to contribution to the exhibition, "Women Artists: The Untold Story (1890-1940)"
Please visit also our Sister Exhibition at Gallery X, titled "Providence to Provincetown: Contemporary Women" (April 15 - May 3, 2015, Opening Reception: April 18, 7-10 PM. For additional information, visit www.galleryx.org.
Contacts: Anna Dempsey (adempsey@umassd.edu) or Allison J. Cywin (acywin@umassd.edu)
- Topical Areas: General Public, University Community, Art Education, Art History, Artisanry, College of Visual and Performing Arts, Fine Arts, Music, Visual Design, Visual Arts, Exhibits
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2:00 PM
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3:00 PM
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BMEBT Seminar Presentation by Ms. Manisha Jassal
- Location: Textiles Building 101E
- Contact: BMEBT Seminar Series
- Description: TOPIC: ELECTROSPUN FIBERS: SMALL SIZE, BIG IMPACT
ABSTRACT:Tissue regeneration relies on building carefully crafted scaffold material in the micron-submicron scale and imparting specific functionality to the scaffold material surface in order to mimic the in vivo environment closely in terms of chemical composition, morphology, and surface functional groups. Fibrous meshes with structural features at the micron-submicron level for ideal 3D tissue regeneration scaffolds can be an inexpensive scale up option. Bio-inert polymers lack the functional motifs for specific bioactivity; however, functionalization of the scaffolds can provide biological functions to actively induce tissue regeneration and promote cell adhesion by targeting specific cell-matrix interactions. It is therefore important to characterize the scaffolds and understand the relationship between the efficacy of the functionalization, the surface properties of the scaffolds, and their biological performance. Another aspect of polymer functionalization is to target controlled drug delivery. Controlled drug delivery is required to improve the therapeutic efficacy of the drug and to reduce the potential toxic effects by delivering the drug at a rate governed by the physiological need of the site of action. Electrospun polymeric fibers have gained wide spread attention as potential drug delivery system because the drug release profile can be controlled by altering scaffold properties as composition, fiber morphology, porosity, surface coating, and form/state of drug molecule. In the current study, poly(caprolactone) (PCL) fibers were fabricated by electrospinning, followed by various treatments to introduce functional groups on the fiber surface. The functionalized electrospun PCL fibers were characterized through scanning electron microscopy, x-ray photoelectron spectroscopy and gel permeation chromatography and the cellular response was studied for these scaffolds. Also, the functional groups introduced via hydrolysis (-COOH) can be ionized by manipulation of pH to impart a negative charge to the fiber surface. Similarly, doxorubicin hydrochloride (DOX), an FDA approved anticancer drug, could be ionized to impart a positive charge at certain pH. The pH-sensitivity of both the materials was utilized to bind DOX electrostatically to the functionalized PCL fibers, with an aim to create pH-responsive drug delivery vehicle for targeted site-specific delivery of DOX. Results indicate successful electrostatic binding of DOX to functionalized electrospun PCL fibers, a high drug payload and the drug delivery response can be modulated by introduction of suitable stimuli (pH in this case). Future work would concentrate on a formulation of a composite drug delivery vehicle combining electrospun scaffolds with poly(vinyl alcohol) (PVA) hydrogels that can release acid near the scaffolds to trigger drug release by changing the pH of the surrounding area.
- Topical Areas: University Community, Biology, College of Engineering
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